大条

(used to modify 事情[shi4 qing5]) serious / grave

see 大夫[dai4 fu5]

big; large; great / older (than another person) / eldest (as in 大姐[da4 jie3]) / greatly; freely; fully / (dialect) father / (dialect) uncle (father's brother)

strip / item / article / clause (of law or treaty) / classifier for long thin things (ribbon, river, road, trousers etc)

to defecate (slang)

thick-skinned / insensitive

(slang) to take a dump