重大

great / important / major / significant

to repeat / repetition / again / re- / classifier: layer

heavy / serious / to attach importance to

see 大夫[dai4 fu5]

big; large; great / older (than another person) / eldest (as in 大姐[da4 jie3]) / greatly; freely; fully / (dialect) father / (dialect) uncle (father's brother)

the implications are profound / the ramifications are huge / (of a decision etc) consequential